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Search Results for " t 9 "

Targets Recommended: TLR

51

抑制剂 & 化合物

7

天然产物

97

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T15017	CU-T12-9	TLR	Immunology/Inflammation
	CU-T12-9 是特异性 TLR1/2激动剂，可激活先天免疫系统和适应性免疫系统。它选择性激活 TLR1/2 异二聚体，可通过促进 TLR1 和 TLR2 二聚而激活 NF-κB 信号，引起下游 TNF-α、IL-10 和 iNOS 增加。
T3450	LX4211 N-4 Intermediate 9 索格列净中间体9,Sotagliflozin Intermediate 9
	LX4211 N-4 Intermediate 9 是 Sotagliflozin 的中间体，Sotagliflozin 是一种口服生物可利用的 SGLT1 和 SGLT2 抑制剂。
T17474	Azide-PEG9-amido-C8-Boc 9-(Azide-PEG9-ethylcarbamoyl)nonanoic t-butyl ester	Others	Others
	Azide-PEG9-amido-C8-Boc is a polyethylene glycol (PEG) derived linker compound utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T17471	Azide-PEG9-amido-C12-Boc 13-(Azide-PEG9-ethylcarbamoyl)tridecanoic t-butyl ester	Others	Others
	Azide-PEG9-amido-C12-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker used for the synthesis of PROTACs[1].
T17442	Amino-PEG9-amido-C16-Boc 17-(Amino-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester	Others	Others
	Amino-PEG9-amido-C16-Boc is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T17473	Azide-PEG9-amido-C4-Boc 5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester	Others	Others
	Azide-PEG9-amido-C4-Boc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T17472	Azide-PEG9-amido-C16-Boc 17-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester	Others	Others
	Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker with utility in PROTAC synthesis [1].
T82758	CDK9-Cyclin T1 PPI-IN-1	CDK	Cell Cycle/Checkpoint
	CDK9-Cyclin T1 PPI-IN-1 (Compound B19) 是CDK9-Cyclin T1蛋白-蛋白相互作用的选择性抑制剂。该化合物能够有效抑制TNBC MDA-MB-231细胞系的细胞增殖(IC50: 0.044 μM)，诱导细胞凋亡，同时降低CDK9的转录活性并减少RNA Pol II CTD ser2的磷酸化，有效地抑制了4T1移植瘤模型小鼠中肿瘤的生长。
T1752	NS6180	Potassium Channel	Membrane transporter/Ion channel
	NS6180是一种高效的KCa3.1离子通道选择性抑制剂，IC50值9nM。NS6180阻止T 细胞活化和炎症反应。
TP1543L	G280-9 acetate(156761-76-1 free base)	Others	Others
	G280-9 acetate(156761-76-1 free base) 是一种常见的黑色素瘤 gp100 表位，受 MHC 相关 HLA-A2 限制。 G280-9 序列是独特的，因为它可以在非常低的浓度下被细胞毒性 T 淋巴细胞识别，但是它显示出低的总免疫原性，这可能是由于该肽对 HLA-A2 的亲和力相对较低。
TQ0174	Mavorixafor AMD-070	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Mavorixafor (AMD-070) 是一种有效的特异性 CXCR4 拮抗剂，对 CXCR4 125I-SDF 结合的 IC50 值为 13 nM。 Mavorixafor 在 MT-4 细胞 (IC50 = 1 nM) 和 PBMC (IC50 = 9 nM) 中抑制 T-tropic HIV-1 (NL4.3 株) 的复制。
T3990	AA26-9	Phospholipase; Serine Protease	Metabolism; Proteases/Proteasome
	AA26-9 是广谱丝氨酸水解酶的高效抑制剂。它的靶点包括丝氨酸肽酶、酰胺酶、脂肪酶、酯酶和硫酯酶。在永生化 T 细胞系，检测到它对 40+ 丝氨酸水解酶中的 1/3 有抑制作用。
T72267	Antitrypanosomal agent 9
	Antitrypanosomal agent 9 是一种有效的抗锥虫体剂。Antitrypanosomal agent 9 显示出对T. b. brucei 的抑制活性，其IC50为 1.15 μM。Antitrypanosomal agent 9 可用于人类非洲锥虫病 (HAT) 研究。
T30215	AUY-954 free base AUY 954,NVP-AUY954,AUY-954,AUY954
	AUY-954 is an effective selective S1P(1) modulator. It can significantly reduce the local expression of EAN rat sciatic nerve T cells, B cells, macrophage infiltration, inflammatory demyelination, interleukin-17 and matrix metalloproteinase-9.
T31672	Erythrofuranosyladenine 9-β-D-Erythrofuranosyladenine,ETA
	Erythrofuranosyladenine(9-beta-D-Erythrofuranosyladenine, ETA) is a nontoxic MTAP substrate. Erythrofuranosyladenine is an effective salvage agent for methylthioadenosine phosphorylase–selective therapy of T-cell acute lymphoblastic leukemia with L-alanos
TP1543	G280-9
	The G280-9 peptide, a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may
T10296	Mavorixafor trihydrochloride AMD-070 trihydrochloride	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM).
TP1416	Gp100 (25-33), human TFA (212370-40-6 free base) Gp100 (25-33), human TFA
	Gp100 (25-33), human TFA is a 25-33 amino acid fragment of human melanoma antigen.Gp100 (25-33), human TFA is a 9-amino acid (AA) epitopes restricted by h-2db and recognized by T cells.
T36743	CDK7/9 tide
	CDK7/9 tide is peptide substrate for CDK7 or CDK9[1]. [1]. Robert T, et, al. Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors. Front Chem. 2020 Feb 27; 8:147.
TP1727	Gp100 (25-33), human
	Gp100 (25-33), human is the amino acids 25-33 fragment of the human melanoma antigen. It is a 9-amino acid (AA) epitope restricted by H-2Db and recognized by the T cells.This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db res
TP1752	GP(33-41)
	GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2Db molecules at the RMA-S (Db Kb) cell surface with a SC50 of 344 nM. GP33-41 Epitopeis a strong agonist of CD8 T cells
T80907	TYVPANASL
	TYVPANASL为由HER2/neu的9个氨基酸组成的MHC I结合CD8 T细胞表位，可用于制备J-LEAPS疫苗。
T79152	PROTAC EGFR degrader 8	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	PROTACEGFRdegrader 8 (T-184) 是一种能够定向降解EGFR的PROTACEGFR降解剂，其在HCC827细胞中的DC50为15.56 nM。该化合物有效抑制多种肺癌细胞系，包括H1975、PC-9和HCC827，其IC50分别为7.72 nM、121.9 nM和14.21 nM。PROTACEGFRdegrader 8 主要用于研究非小细胞肺癌（NSCLC）。
T80906	TYVPANASL TFA
	TYVPANASL TFA，一种由HER2/neu的9个氨基酸组成，可结合MHC I并与CD8 T细胞表位相关的化合物。该化合物可用于制备J-LEAPS疫苗。
T38107	JJH260 JJH260
	JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value of 0.57 μM. JJH260 also inhibits the novel FAHFA hydrolase androgen-dependent TFPI-regulating protein (ADTRP; IC50 = 8.5 μM), as well as the serine hydrolase ABHD6 and the lysophospholipases LYPLA1 and LYPLA2. JJH260 inhibits the FAHFA hydrolase activity of LNCaP and T cell lysa...
T64280	ODN 2216
	ODN 2216 是一种 TLR9 (toll-like receptor 9) 配体或激动剂，能够诱导产生大量的 IFN-α 和 IFN-β。ODN 2216 可以利用 pDC (浆细胞样 DC) 诱导 IFN-α，以及利用 DC (树突状细胞) 产生IL-12 (p40)。ODN 2216 能够间接的、在 IFN-α/β 介导下刺激外周血单核细胞 (PBMC) 产生 IFN-γ。ODN 2216 可以激活 NK 细胞，诱导 IFN-γ 产生 TCR 触发的 CD4+T 细胞。
TP1501	CTTHWGFTLC, CYCLIC
	This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of t
T36412	Multiflorenol
	Multiflorenol is a triterpene that has been found in T. kirilowii seeds.1 It inhibits in vitro activation of Epstein-Barr virus early antigen (EBV-EA) induced by the tumor promoter phorbol 12-myristate 13-acetate in a concentration-dependent manner. \|1. Akihisa, T., Tokuda, H., Ichiishi, E., et al. Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines. Cancer Lett. 173(1), 9-14 (2001).
T78702	PTP1B/AKR1B1-IN-1	Phosphatase	Metabolism
	PTP1B/AKR1B1-IN-1是一种针对PTP1B和AKR1B1的双重抑制剂，其IC50值分别为0.06 μM和4.3 μM。该化合物也能抑制TC-PTP，IC50为9 μM。在小鼠成肌细胞中，PTP1B/AKR1B1-IN-1作为胰岛素模拟剂使用，并能减少AKR1B1依赖的山梨醇积累，有助于抑制2型糖尿病的发展并控制血糖水平。
T38135	3,4-Dehydro Cilostazol
	3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol. 3,4-Dehydro Cilostazol is used for pharmacokinetic study[1]. [1]. T R S Satheeshmanikandan, et al. Liquid Chromatography - Tandem Mass Spectrometry for the Simultaneous Quantitation of Glipizide, Cilostazol and Its Active Metabolite 3, 4-dehydro-cilostazol in Rat Plasma: Application for a Pharmacokinetic Study. Arzneimittelforschung. 2012 Sep;62(9):425-32.
T70988	Ibulocydine
	Ibulocydine is a potent CDK inhibitor. Ibulocydine has high activity against Cdk7/cyclin H/Mat1 and Cdk9/cyclin T. Ibulocydine inhibited the growth of HCC cells more effectively than other Cdk inhibitors, including olomoucine and roscovitine, whereas ibulocydine as well as the other Cdk inhibitors and BMK-Y101 minimally influenced the growth of normal hepatocyte cells. Ibulocydine induced apoptosis in HCC cells, most likely by inhibiting Cdk7 and Cdk9. In vitro treatment of HCC cells with ibuloc...
T38381	CAY17c
	CAY17c is an inhibitor of bromodomain-containing protein 4 (BRD4; IC50= 0.71 μM), as well as class I histone deacetylases (HDACs; IC50s = 0.046, 0.058, 0.075, and 0.167 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 0.073 and 0.923 μM for HDAC6 and HDAC10, respectively).1It is selective for these enzymes over BRD2, -3, and -T (IC50s = >20 μM for all), as well as over HDAC4, -5, -7, -9, and -11 (IC50s = >10 μM for all). CAY17c inhibits the proliferation of HCT116, SW620,...
T37553	(-)-Mycousnine
	(-)-Mycousnine is a microbial metabolite and derivative of usnic acid originally isolated fromM. nawaethat has antibacterial and antifungal activities.1,2It is active against the Gram-positive bacteriaB. subtilis,K. rhizophila, andS. aureus(MICs = 4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteriaE. coli,S. typhimurium, andK. pneumoniae(MICs = >128 g/ml for all).2(-)-Mycousnine is also active against the fungiT. mentagrophytes,T. rubrum, andC. albicans(MICs = 25, 25, and 100 μg/m...
T37176	Edoxaban impurity 6
	Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2]. [1]. Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9.[2]. Mendell J, Lee F, Chen S, The Effe...
T35978	Benastatin A
	Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 μM for the rat liver enzyme).2Benastatin A is active against several bacteria, including methicillin-resistantS. aureus(MRSA; MIC = 3.12 μg/ml). It induces apoptosis and cell cycle arrest at the G1/G0phase in Colon 26 mouse colon cancer cells when used at concentrations of 20 and 16 μM, respectively.3 1.Xu, Z., Sch...
T35680	2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide
	2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gram-positive bacteriaS. aureus,M. luteus, andB. cereus(MICs = 130, 100, and 50 μg/ml, respectively), and the fungiC. albicans,G. candidum,T. rubrum,F. oxysporum,A. flavus, andS. brevicaulis(MICs = 69-120 μg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a prec...
T37002	7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)
	7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F) is a thiol-reactive fluorogenic probe.1It has been used to quantify the levels of homocysteine, cysteine, and cysteamine in human plasma.2SBD-F displays excitation/emission maxima of 380/515 nm, respectively.1 1.Imai, K., Toyo’oka, T., and Watanabe, Y.A novel fluorogenic reagent for thiols: Ammonium 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonateAnal. Biochem.128(2)471-473(1983) 2.Ichinose, S., Nakamura, M., Maeda, M., et al.A validated HPLC-fluoresc...
T37692	Piericidin B
	Piericidin B is a bacterial metabolite that has been found inS. mobaraensisand has insecticidal and antimicrobial activities.1,2,3It inhibits NADH oxidase activity in isolated bovine heart mitochondria and inhibits respiration in isolated rat liver mitochondria and isolated cockroach (P. americana) muscle mitochondria.2,3Topical application of piericidin B (4 μg/insect) induces mortality in 87.5% of houseflies (M. domestica).1It induces 93.3, 100, and 100% mortality in rice stem borer (C. simple...
T35573	Adenosine 5’-methylenediphosphate (hydrate)
	Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or adenosine 5’-triphosphate but not adenosine in VA-13 human fibroblasts when used at a concentration of 100 μM. Adenosine 5’-methylenediphosphate reduces proliferation of U138MG glioma cells, as well as inhibits the invasion and migration of MHCC97H hepatocellular carcinoma (HCC) ...
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius.2β-Defensin-2 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes.3It also stimulates calcium mobilization, migration, and proliferation of keratinocytes whe...
T37861	Talabostat
	Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 and some other DASH family enzymes essentially as potently as it inhibits DPP-IV[1]. Talabostat stimulates the immune system by triggering a proinflammatory form of cell death in monocytes and macrophages known as pyroptosis. The inhibition of two serine proteases, DPP8 and DPP9,...
T37178	Norhyodeoxycholic Acid
	Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid .1,2 NHDCA is an intermediate in the synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of δ5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.3 \|1. Schteingart, C.D., and Hofmann, A.F. Synthesis of 24-nor-5β-cholan-23-oic acid derivatives: A convenient and efficient one-carbon ...
T35504	(±)10-HDHA
	(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.[1][2] It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.[3][4][5] (±)10-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid. Reference：[1]. VanRollins, M., and Murphy, R.C. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate. J. Lipid Res. 25(5), 507-517 (1984).[2]. Reynaud, ...
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...
T36199	AZD 1152 (hydrochloride)
	AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5 1.Mortlock, A.A., Foote, K.M., Heron, N.M., et al.Discovery, synthesis, and in vivo activity of a new class of p...
T35799	MBX-8025 (sodium salt)
	MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increases in fasting blood glucose and serum insulin levels, and decreases insulin resistance in Alms1 mutant (foz/foz) mice fed an atherogenic diet as a model of diet-induced obesity, type 2 diabetes, and non-alcoholic steatohepatitis (NASH).2 It also decreases serum alanine transamin...
T35517	4-deoxy Nivalenol-13C15 4-deoxy Nivalenol-13C15
	4-deoxy Nivalenol-13C15is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.2It induces leth...
T35789	Palmitic acid-1-13C
	Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 \|1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T36639	Donecopride (fumarate hydrate)
	Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= 3,530 nM) but does bind to 5-HT2Band sigma-2 (σ2) receptors (Ki= 1.6 nM for both) in a panel of 42 neurotransmitter receptors and transporters. Donecopride induces release of soluble amyloid precursor protein-α (sAPP-α) in COS-7 cells transiently expressing 5-HT4with an EC50value...
T36570	KUS121
	KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, an inducer of ER stress, in HeLa cells when used at concentrations of 20, 50, and 50 μM, respectively. KUS121 (100 μM) inhibits ATP depletion and cell death induced by oxygen-glucose deprivation (OGD) in rat primary cortical neurons in anin vitromodel of cerebral ischemia.2It red...

化合物

Cat.No: T15017

Target: TLR

LX4211 N-4 Intermediate 9

Cat.No: T3450

Synonym: 索格列净中间体9,Sotagliflozin Intermediate 9

Azide-PEG9-amido-C8-Boc

Cat.No: T17474

Synonym: 9-(Azide-PEG9-ethylcarbamoyl)nonanoic t-butyl ester

Target: Others

Azide-PEG9-amido-C12-Boc

Cat.No: T17471

Synonym: 13-(Azide-PEG9-ethylcarbamoyl)tridecanoic t-butyl ester

Target: Others

Amino-PEG9-amido-C16-Boc

Cat.No: T17442

Synonym: 17-(Amino-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester

Target: Others

Azide-PEG9-amido-C4-Boc

Cat.No: T17473

Synonym: 5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester

Target: Others

Azide-PEG9-amido-C16-Boc

Cat.No: T17472

Synonym: 17-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester

Target: Others

CDK9-Cyclin T1 PPI-IN-1

Cat.No: T82758

Target: CDK

Cat.No: T1752

Target: Potassium Channel

G280-9 acetate(156761-76-1 free base)

Cat.No: TP1543L

Target: Others

Cat.No: TQ0174

Synonym: AMD-070

Target: CXCR

Cat.No: T3990

Target: Phospholipase, Serine Protease

Antitrypanosomal agent 9

Cat.No: T72267

AUY-954 free base

Cat.No: T30215

Synonym: AUY 954,NVP-AUY954,AUY-954,AUY954

Erythrofuranosyladenine

Cat.No: T31672

Synonym: 9-β-D-Erythrofuranosyladenine,ETA

Cat.No: TP1543

Mavorixafor trihydrochloride

Cat.No: T10296

Synonym: AMD-070 trihydrochloride

Target: HIV Protease

Gp100 (25-33), human TFA (212370-40-6 free base)

Cat.No: TP1416

Synonym: Gp100 (25-33), human TFA

Cat.No: T36743

Gp100 (25-33), human

Cat.No: TP1727

Cat.No: TP1752

Cat.No: T80907

PROTAC EGFR degrader 8

Cat.No: T79152

Target: EGFR

Cat.No: T80906

Cat.No: T38107

Synonym: JJH260

Cat.No: T64280

CTTHWGFTLC, CYCLIC

Cat.No: TP1501

Cat.No: T36412

PTP1B/AKR1B1-IN-1

Cat.No: T78702

Target: Phosphatase

3,4-Dehydro Cilostazol

Cat.No: T38135

Cat.No: T70988

Cat.No: T38381

Cat.No: T37553

Edoxaban impurity 6

Cat.No: T37176

Cat.No: T35978

2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide

Cat.No: T35680

7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)

Cat.No: T37002

Cat.No: T37692

Adenosine 5’-methylenediphosphate (hydrate)

Cat.No: T35573

β-Defensin-2 (human) (trifluoroacetate salt)

Cat.No: T35451

Cat.No: T37861

Norhyodeoxycholic Acid

Cat.No: T37178

Cat.No: T35504

Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

AZD 1152 (hydrochloride)

Cat.No: T36199

MBX-8025 (sodium salt)

Cat.No: T35799

4-deoxy Nivalenol-13C15

Cat.No: T35517

Synonym: 4-deoxy Nivalenol-13C15

Palmitic acid-1-13C

Cat.No: T35789

Donecopride (fumarate hydrate)

Cat.No: T36639

Cat.No: T36570

Cat. No.	Product Name	Target	Signaling Pathways
TN7037	(Z)-9-nonadecene 9-Nonadecene	Others	Others
	(Z)-9-nonadecene (9-Nonadecene) 首次在 T. melanocephalum 中被发现。它是下颌腺中的主要成分，而虹膜在尾腺中产生。
T75632	Ganoderic acid T1
	Ganoderic acid T1是Ganoderic acid T的去乙酰化衍生物，具有促进癌细胞凋亡(apoptosis)的功能。它通过降低线粒体膜电位以及激活caspase-9和caspase-3来引发细胞凋亡，并增加细胞内ROS的产生，从而表现出促氧化活性和细胞性毒作用，同时减弱抗氧化防御系统。
TN5033	Skullcapflavone I	IL Receptor; Caspase; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...
T36438	Sporogen-AO 1
	Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO 1 is cytotoxic to HeLa, KB, and NCI H187 cancer cells (IC50s = 8.3, 9, and 5.1 μM, respectively).2,5It is active againstC. albicans(MIC = 4 mM).3 1.Tanaka, S., Wada, K., Marumo, S., et al.Structure of sporogen-ao 1, a sporogenic substance of Aspergillus oryzaeTetrahedron Lett.25(...
T36348	Cerebroside C
	Cerebroside C is a fungal metabolite and glycosphingolipid that has been found in the rice pathogenic fungusM. grisea.1It induces production of the phytoalexin momilactone A when applied to wounded rice leaves, indicating that cerebroside C is an elicitor of the hypersensitive response in rice. Cerebroside C increases germination rate and reduces germination time in wheat seeds in a concentration-dependent manner at 4°C.2It also increases root length, fresh weight, and dry weight of wheat seedli...
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...

天然产物

(Z)-9-nonadecene

Cat.No: TN7037

Synonym: 9-Nonadecene

Target: Others

Ganoderic acid T1

Cat.No: T75632

Skullcapflavone I

Cat.No: TN5033

Target: IL Receptor, Caspase, Prostaglandin Receptor

9(S),12(S),13(S)-TriHOME

Cat.No: T37272

Cat.No: T36438

Cat.No: T36348

Cat.No: T37452

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc) WUCAM,VSTM3,VSIG9,T cell immunore...	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05096	Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc) CD71,T9,transferrin recept	Human	HEK293
	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system...
TMPY-01873	Transferrin Receptor/TFRC Protein, Human, Recombinant (His) TFR1,p90,CD71,TFR,transf...	Human	HEK293
	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system...
TMPY-01897	PRSS3 Protein, Human, Recombinant (His) PRSS4,TRY4,TRY3,RP11-176F3.3,T	Human	HEK293
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPK-00568	IL-9 Protein, Cynomolgus, Recombinant (His) P40,HP40,IL-9,T-cell growth fac	Cynomolgus	HEK293
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.
TMPK-00026	IL-9 Protein, Mouse, Recombinant (hFc) P40,IL-9,Interleukin-9,Cyt	Mouse	HEK293
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.
TMPK-00025	IL-9 Protein, Human, Recombinant (hFc) HP40,Cytokine P40,白细胞介素,Interleukin-9<...	Human	HEK293
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.
TMPY-01804	CD229 Protein, Mouse, Recombinant (His) T100,SLAMF3,CD229,AI893573,Lgp100...	Mouse	HEK293
	CD229 Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 46.5 kDa. Accession number: Q01965
TMPJ-00359	SLAMF3 Protein, Human, Recombinant (His) Signaling lymphocytic activation ...	Human	Human Cells
	SLAMF3 (CD229) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Mature human SLAMF3 consists of a 407 amino acid (aa) extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains. The ECD of human SLAMF3 shares 57% - 59% aa sequence identity with mouse and rat SLAMF3. Within the first two Ig-like domains that are common to all SLAM proteins, human SLAMF3 shares 24% - 39% aa sequence identity with human 2B4, BLAME, CD2F-10, CD84, CRACC, ...
TMPJ-00378	Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His) p90,TfR,T9,Trfr...	Human	Human Cells
	Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o...
TMPJ-01154	SLAMF3 Protein, Mouse, Recombinant (His) SLAM family member 3,T-lymphocyte surface ...	Mouse	Human Cells
	CD229(SLAMF3) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Mature mouse CD229 consists of a 406 aa extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains, a 21 aa transmembrane segment, and a 180 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs ITSMs. Within the first two Ig-like domains that are common to all SLAM proteins, mouse CD229 shares 22%-36% aa sequence identity with mouse 2B4, BLAME, CD2F10,...
TMPK-00376	Transferrin R/CD71 Protein, Human, Recombinant (hFc) sTfR,CD71,TfR1,TFR,p90,<...	Human	HEK293
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPJ-00143	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated ILA,4-1BB ligand receptor,T-cell ant	Human	Human Cells
	Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.
TMPJ-00140	4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated CD137,CDw137,4-1BB ligand receptor,ILA,T-c...	Cynomolgus	Human Cells
	Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.
TMPY-06462	TIGIT Protein, Human, Recombinant (aa 22-141, His) T cell immunoreceptor with Ig and...	Human	CHO
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-06213	TIGIT Protein, Human, Recombinant (aa 1-141, His) T cell immunoreceptor with Ig and...	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-06300	TIGIT Protein, Human, Recombinant (His & Avi), Biotinylated WUCAM,T cell immunoreceptor with ...	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-06135	TIGIT Protein, Human, Recombinant (hFc & Avi), Biotinylated WUCAM,T cell immunoreceptor with ...	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05121	TIGIT Protein, Human, Recombinant (hFc), Biotinylated T cell immunoreceptor with Ig and...	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPJ-00144	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His) CD137,4-1BB ligand receptor,T-cell ant...	Human	Human Cells
	Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.
TMPJ-00142	4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His) CDw137,ILA,4-1BB ligand receptor,T-cell an...	Cynomolgus	Human Cells
	Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by...
TMPJ-00141	4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) 4-1BB ligand receptor,CD137,CDw137,ILA,TNF...	Cynomolgus	Human Cells
	Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by...
TMPY-06134	TIGIT Protein, Human, Recombinant (mFc) VSTM3,VSIG9,WUCAM,T cell immunore...	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05122	TIGIT Protein, Human, Recombinant (His), Biotinylated VSTM3,VSIG9,T cell immunorecep	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPK-01261	Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) TFR,T9,CD71,TfR1,sT<...	Cynomolgus	HEK293
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPK-00375	Transferrin R/CD71 Protein, Human, Recombinant (His & Avi), Biotinylated TFRC,sTfR,T9,p9...	Human	HEK293
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPK-00374	Transferrin R/CD71 Protein, Human, Recombinant (His & Avi) p90,TFR,sTfR,T9...	Human	HEK293
	The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPK-00357	CD229 Protein, Human, Recombinant (His & Avi) LY9,T100,AI893573,SLAMF3,Lgp100,C...	Human	HEK293
	CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells.
TMPY-05617	Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated TRFR,p90,TR,TFR,CD71,	Human	HEK293
	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system...
TMPK-00358	CD229 Protein, Human, Recombinant (His & Avi), Biotinylated T100,Lgp100,LY9,AI893573,CD22...	Human	HEK293
	CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells.
TMPJ-00629	TIGIT Protein, Cynomolgus, Recombinant (His) VSTM3,V-set and transmembrane dom...	Cynomolgus	Human Cells
	T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM), and is expressed on regulatory, memory, activated T cells and NK cells. TIGIT binds to CD155(PVR) that appear on dendritic cells (DC), macrophages and endothelium with high affinity, and CD112(PVRL2) with lower...
TMPK-00148	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated TNFRSF9,FLJ43501,4-1BB,4-1BB ligand recep<...	Human	HEK293
	4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
TMPK-00147	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi) T cell antigen ILA,ILA,4-1BB ligand recep<...	Human	HEK293
	4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
TMPY-00599	Influenza A H7N9 (A/Shanghai/4664T/2013) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H7N9	Baculovirus-Insect Cells
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPJ-00139	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) 4-1BBL,Tumor necrosis factor ligand superf...	Human	E. coli
	Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/...
TMPY-05227	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated TIMD3,hepatitis A virus cellular ...	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specifically identifies Th1 cells in both the mouse and human. Recently, the identification of Galectin-9 as a ligand for TIM-3 has established the TIM-3-Galectin-9 pathway as an important regulator of Th1 immunity and toleranc...
TMPY-01621	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) TIMD-3,hepatitis A virus cellular...	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specifically identifies Th1 cells in both the mouse and human. Recently, the identification of Galectin-9 as a ligand for TIM-3 has established the TIM-3-Galectin-9 pathway as an important regulator of Th1 immunity and toleranc...
TMPY-01870	IL-9 Protein, Human, Recombinant (His) P40,interleukin 9,HP40,白细胞介素,IL-9...	Human	Baculovirus-Insect Cells
	Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. Genetic studies on a mouse model of asth...
TMPY-03383	IL-7 Protein, Human, Recombinant IL-7,interleukin 7,Interleukin-7,白介素,白细胞介素	Human	E. coli
	IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell recep...
TMPY-00524	IL-7 Protein, Mouse, Recombinant Il-7,A630026I06Rik,interleukin 7,hlb368	Mouse	E. coli
	IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell recep...
TMPY-05345	TIGIT Protein, Cynomolgus, Recombinant (hFc) T cell immunoreceptor with Ig and...	Cynomolgus	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-02669	TIGIT Protein, Mouse, Recombinant (His) T cell immunoreceptor with Ig and...	Mouse	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-02234	CXCL9 Protein, Human, Recombinant MIG,CMK,Humig,chemokine (C-X-C motif) ligand 9<...	Human	E. coli
	Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defined; however, it is thought to be involved in T cell trafficking. CXCL9/MIG functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. CXCL9/MIG, together with CXCL10 and CXCL11, may activate CXCR3 by bi...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His) VEGFA,VEGF-A,Vascular permeability factor,...	Human	Human Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...
TMPY-03698	VEGF121b Protein, Human, Recombinant MVCD1,VEGF,VPF,vascular endothelial growth...	Human	HEK293
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per...
TMPH-00005	YAP1 Protein, Human, Recombinant (Isoform 9, His) YAP1-2delta	Human	Yeast
	YAP1 Protein, Human, Recombinant (Isoform 9, His) is expressed in Yeast with C-terminal 6xHis tag. The predicted molecular weight is 56.4 kDa. Accession number: P46937-9
TMPJ-01455	Galectin-9 Protein, Human, Recombinant (His) LGALS9,Tumor Antigen HOM-HD-21,Ec...	Human	Human Cells
	Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses t...
TMPK-00128	CD7 Protein, Human, Recombinant (His & Avi), PE-Labeled LEU-9,TP41,CD7 molecule,Tp40,CD7,...	Human	HEK293
	CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells.
TMPJ-00203	Galectin-9 Protein, Human, Recombinant (GST) Gal-9delta5,Ecalectin,LGALS9<...	Human	E. coli
	Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses t...
TMPJ-00659	Galectin-9 Protein, Mouse, Recombinant (GST) Gal-9,Galectin-9,Lgals9	Mouse	E. coli
	Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses t...
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重组蛋白

TIGIT Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04970

Species: Human

Expression System: HEK293

Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05096

Species: Human

Expression System: HEK293

Transferrin Receptor/TFRC Protein, Human, Recombinant (His)

Cat.No: TMPY-01873

Species: Human

Expression System: HEK293

PRSS3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01897

Species: Human

Expression System: HEK293

IL-9 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00568

Species: Cynomolgus

Expression System: HEK293

IL-9 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00026

Species: Mouse

Expression System: HEK293

IL-9 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00025

Species: Human

Expression System: HEK293

CD229 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01804

Species: Mouse

Expression System: HEK293

SLAMF3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00359

Species: Human

Expression System: Human Cells

Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)

Cat.No: TMPJ-00378

Species: Human

Expression System: Human Cells

SLAMF3 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01154

Species: Mouse

Expression System: Human Cells

Transferrin R/CD71 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00376

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated

Cat.No: TMPJ-00143

Species: Human

Expression System: Human Cells

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00140

Species: Cynomolgus

Expression System: Human Cells

TIGIT Protein, Human, Recombinant (aa 22-141, His)

Cat.No: TMPY-06462

Species: Human

Expression System: CHO

TIGIT Protein, Human, Recombinant (aa 1-141, His)

Cat.No: TMPY-06213

Species: Human

Expression System: HEK293

TIGIT Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06300

Species: Human

Expression System: HEK293

TIGIT Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06135

Species: Human

Expression System: HEK293

TIGIT Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05121

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00144

Species: Human

Expression System: Human Cells

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00142

Species: Cynomolgus

Expression System: Human Cells

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-00141

Species: Cynomolgus

Expression System: Human Cells

TIGIT Protein, Human, Recombinant (mFc)

Cat.No: TMPY-06134

Species: Human

Expression System: HEK293

TIGIT Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05122

Species: Human

Expression System: HEK293

Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01261

Species: Cynomolgus

Expression System: HEK293

Transferrin R/CD71 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00375

Species: Human

Expression System: HEK293

Transferrin R/CD71 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00374

Species: Human

Expression System: HEK293

CD229 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00357

Species: Human

Expression System: HEK293

Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05617

Species: Human

Expression System: HEK293

CD229 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00358

Species: Human

Expression System: HEK293

TIGIT Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00629

Species: Cynomolgus

Expression System: Human Cells

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated

Cat.No: TMPK-00148

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi)

Cat.No: TMPK-00147

Species: Human

Expression System: HEK293

Influenza A H7N9 (A/Shanghai/4664T/2013) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-00599

Species: H7N9

Expression System: Baculovirus-Insect Cells

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00139

Species: Human

Expression System: E. coli

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05227

Species: Human

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01621

Species: Human

Expression System: HEK293

IL-9 Protein, Human, Recombinant (His)

Cat.No: TMPY-01870

Species: Human

Expression System: Baculovirus-Insect Cells

IL-7 Protein, Human, Recombinant

Cat.No: TMPY-03383

Species: Human

Expression System: E. coli

IL-7 Protein, Mouse, Recombinant

Cat.No: TMPY-00524

Species: Mouse

Expression System: E. coli

TIGIT Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-05345

Species: Cynomolgus

Expression System: HEK293

TIGIT Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02669

Species: Mouse

Expression System: HEK293

CXCL9 Protein, Human, Recombinant

Cat.No: TMPY-02234

Species: Human

Expression System: E. coli

VEGF121 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00865

Species: Human

Expression System: Human Cells

VEGF121b Protein, Human, Recombinant

Cat.No: TMPY-03698

Species: Human

Expression System: HEK293

YAP1 Protein, Human, Recombinant (Isoform 9, His)

Cat.No: TMPH-00005

Species: Human

Expression System: Yeast

Galectin-9 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01455

Species: Human

Expression System: Human Cells

CD7 Protein, Human, Recombinant (His & Avi), PE-Labeled

Cat.No: TMPK-00128

Species: Human

Expression System: HEK293

Galectin-9 Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00203

Species: Human

Expression System: E. coli

Galectin-9 Protein, Mouse, Recombinant (GST)

Cat.No: TMPJ-00659

Species: Mouse

Expression System: E. coli

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